During the first wave of Corona, abdominal pain, diarrhea, and loss of appetite were the main symptoms of infected patients. One study found that up to 34 percent of COVID patients experience diarrhea.
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NIH According to a research team funded by COVID There is an imbalance in the microbiome of the patients’ gut, which allows antibiotic-resistant bacterial infections to dominate the body. One thing to keep in mind is that disturbances in the gut microbiome due to external microbes can cause serious illness in patients, disrupting their routine lives. The human intestinal system (gut system) is quite extensive and diverse. It contains 0 million to 100 trillion microorganisms and their genes gastrointestinal tract (GI) controls.
Dr. Om Srivastava, Co-Director, Department of Infectious Diseases, Sir HN Reliance Foundation Hospital, Mumbai, said that there are many reasons for antimicrobial resistance (AMR) in our country.
Dr Srivastava said, “Mostly, it is due to the wrong use of antibiotics. If a person has common cold or upset stomach, they immediately take antibiotics. But is it the right medicine for that ailment? Is the dosage of the medicine taken correctly? Patients in a hurry do not consider these things. The symptoms of these diseases last for two-three days and when the patient stops seeing the symptoms, he stops taking the medicine without completing the entire course. This makes the patient resistant to the next disease. In other words, the inappropriate use of antibiotics, the inappropriate duration, and the inappropriate combination are responsible for the current AMR.”
Many other bacterial infections can occur in the intestine due to COVID-19
Researchers investigated how the coronavirus affects gut microbes in mice. The study, published in Nature Communications in November, found that COVID causes an imbalance in the patient’s gut microbiome, which leads to antibiotic-resistant bacterial infections. Therefore, the research suggested that a patient with a coronavirus infection is at a higher risk of developing other bacterial infections in the intestine. The digestive system is also greatly affected by COVID.
During the first wave of COVID, abdominal pain, diarrhea, and loss of appetite were the main symptoms of infected patients. One study found that up to 34 percent of COVID patients experience diarrhea.
Studies have shown that the coronavirus enters intestinal cells using the angiotensin-converting enzyme 2 (ACE-2) protein as a receptor. Once inside, it makes copies of its viral proteins by replicating them.
The report states that most gastrointestinal (GI) symptoms associated with COVID-19 are mild and self-limiting, and include anorexia, diarrhea, anorexia, vomiting, and abdominal pain/discomfort.
There is increasing evidence for the involvement of the gastrointestinal tract in the severity of COVID. A study by The Chinese University of Hong Kong that examined blood, stool, and patient records of 100 people found that patients with COVID had a significantly altered gut microbiome composition compared to non-COVID individuals, even though Whether patients have taken medicine or not.
The study found that due to COVID, there was a significant reduction in gut bacteria with known immunomodulatory potential such as Faecalibacterium prausnitzii, Eubacterium rectale and several other bifidobacterial species.
Increased Antimicrobial Resistance During COVID-19
In a webinar organized by the Tata Institute for Genetics and Society (TIGS), scientists and clinicians said that there has been a significant increase in AMR due to COVID-19, and the current pandemic has greatly affected antimicrobial management, as well as AMR The work to be done towards preventing and controlling has been pushed back years.
TIGS director, Dr Rakesh Mishra, highlighted that AMR is “probably creating a silent tsunami, and could take us to the very worst in no time.” He cautioned that the pandemic does not mean that other problems have disappeared.
Dr Mishra said one of the reasons for misuse is in healthcare settings for humans, but “misuse or overuse of antibiotics in livestock, fisheries, and poultry” is also a huge reason. Lack of access to clean water, sanitation, and hygiene also increases the risk of AMR worldwide. WHO has declared AMR as one of the top 10 global health threats.
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Source: www.tv9hindi.com”